Intake out of Potassium, Magnesium, Calcium, and you will Soluble fiber and you will Risk of Coronary attack Among us Boys
In the Departments out of Nutrition (An excellent.Good., Age.B.Roentgen., E.L.G., M.J.S., W.C.W.), Epidemiology (A.A great., Elizabeth.B.R., M.A beneficial.H., M.J.S., W.C.W.), and you will Health insurance and Personal Choices (I.K.), Harvard College or university from Societal Health, additionally the Channing Research, Agencies from Treatments, Harvard Scientific School and you can Brigham and you can Women’s Healthcare (Elizabeth.B.R., E.L.G., Meters.J.S., W.C.W., We.K.), Boston, Size.
Intake out-of Potassium, Magnesium, Calcium supplements, and you can Fiber and you will Threat of Heart attack Among us Boys
Throughout the Departments of Nutrition (A good.A., E.B.Roentgen., E.L.G., M.J.S., W.C.W.), Epidemiology (A great.A., Elizabeth.B.R., M.A great.H., Yards.J.S., W.C.W.), and you can Health insurance and Public Behavior (We.K.), Harvard University regarding Societal Health, while the Channing Laboratory, Department regarding Drug, Harvard Medical University and you will Brigham and Ladies Healthcare (Elizabeth.B.Roentgen., E.L.G., Meters.J.S., W.C.W., I.K.), Boston, Mass.
Intake away from Potassium, Magnesium, Calcium, and you can Dietary 
fiber and you will Threat of Heart attack In our midst Males
About Divisions regarding Diet (Good.A great., Elizabeth.B.R., Elizabeth.L.G., Meters.J.S., W.C.W.), Epidemiology (A.An effective., E.B.R., Yards.A.H., M.J.S., W.C.W.), and you will Health insurance and Social Behavior (I.K.), Harvard School off Social Fitness, and Channing Research, Company from Drug, Harvard Scientific School and you will Brigham and you will Ladies’ Health (Age.B.R., Elizabeth.L.G., M.J.S., W.C.W., I.K.), Boston, Mass.
Consumption of Potassium, Magnesium, Calcium, and Soluble fiber and Risk of Coronary attack In our midst Men
On the Departments out of Nourishment (Good.A., E.B.Roentgen., Elizabeth.L.G., M.J.S., W.C.W.), Epidemiology (A great.A great., Age.B.Roentgen., Meters.A good.H., M.J.S., W.C.W.), and you can Health and Social Choices (I.K.), Harvard School regarding Public Wellness, and Channing Research, Service from Treatments, Harvard Scientific College or university and you will Brigham and Ladies’ Healthcare (E.B.Roentgen., E.L.Grams., Meters.J.S., W.C.W., We.K.), Boston, Bulk.
Consumption from Potassium, Magnesium, Calcium supplements, and you can Soluble fiber and Danger of Coronary attack In our midst Boys
Regarding Departments away from Nutrients (A good.A good., Age.B.Roentgen., Age.L.Grams., M.J.S., W.C.W.), Epidemiology (A beneficial.An effective., E.B.Roentgen., Meters.An excellent.H., M.J.S., W.C.W.), and you can Health insurance and Public Choices (I.K.), Harvard College away from Societal Fitness, as well as the Channing Lab, Institution regarding Medication, Harvard Medical School and Brigham and you may Ladies Hospital (E.B.Roentgen., Elizabeth.L.Grams., Meters.J.S., W.C.W., We.K.), Boston, Mass.
Consumption of Potassium, Magnesium, Calcium, and you will Fibre and you may Likelihood of Coronary attack In our midst Men
On the Departments from Nourishment (An effective.A great., Elizabeth.B.R., E.L.G., Meters.J.S., W.C.W.), Epidemiology (A great.A good., Elizabeth.B.R., Yards.An excellent.H., M.J.S., W.C.W.), and you can Health and Personal Choices (I.K.), Harvard College regarding Personal Wellness, in addition to Channing Laboratory, Company out-of Treatments, Harvard Scientific School and Brigham and you will Women’s Health (E.B.Roentgen., E.L.G., Yards.J.S., W.C.W., We.K.), Boston, Size.
Intake away from Potassium, Magnesium, Calcium supplements, and Dietary fiber and you can Threat of Stroke Among us Males
Throughout the Divisions out of Nutrients (A good.An effective., Elizabeth.B.Roentgen., E.L.G., Meters.J.S., W.C.W.), Epidemiology (A good.Good., Elizabeth.B.R., Yards.A good.H., Meters.J.S., W.C.W.), and you will Health and Societal Choices (We.K.), Harvard College of Societal Wellness, in addition to Channing Lab, Agency of Drug, Harvard Medical College and you can Brigham and you will Women’s Healthcare (E.B.Roentgen., Elizabeth.L.Grams., Yards.J.S., W.C.W., We.K.), Boston, Size.
Abstract
Background-Animal experiments and epidemiological studies have recommended you to definitely highest potassium intake may slow down the danger of coronary arrest, however the facts is inconclusive, additionally the part out-of almost every other nourishment inside the potassium-steeped dinners remains unknown.
Tips and Overall performance-We looked at the fresh association of potassium and you can associated diet having risk out of heart attack among 43 738 You males, forty so you can 75 years old, instead of recognized aerobic diseases otherwise diabetes, which done a beneficial semiquantitative eating volume questionnaire inside the 1986. Through the 8 numerous years of follow-upwards, 328 strokes (210 ischemic, 70 hemorrhagic, forty eight unspecified) were reported. The brand new multivariate relative likelihood of coronary arrest of any type for males on best 5th from potassium consumption (average intake, cuatro.step 3 grams/d) versus those who work in the base (median, dos.cuatro g/d) try 0.62 (95% CI, 0.43, 0.88; P having development=0.007). Outcomes for ischemic coronary attack alone was comparable. Intakes out-of cereal dietary fiber and you can magnesium, however out-of calcium, was along with inversely for the likelihood of overall heart attack. This type of inverse associations was in fact all the more powerful into the hypertensive than normotensive males and just weren’t materially changed by adjustment for blood pressure. Entry to potassium supplements was also inversely related to risk of heart attack, like among people getting diuretics (cousin exposure, 0.36; 95% CI, 0.18, 0.72).
Conclusions-Even in the event these types of research don’t establish an effective causal dating, they are similar to the hypothesis one to dieting full of potassium, magnesium, and you may cereal soluble fiber reduce the risk of coronary attack, including one of hypertensive people. Potassium medicine can certainly be useful, however, because of problems, use might be very carefully tracked and limited to men bringing potassium-dropping diuretics.